Nebulization of the acidified sodium nitrite formulation attenuates acute hypoxic pulmonary vasoconstriction
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چکیده
منابع مشابه
Nebulization of the acidified sodium nitrite formulation attenuates acute hypoxic pulmonary vasoconstriction
BACKGROUND Generalized hypoxic pulmonary vasoconstriction (HPV) occurring during exposure to hypoxia is a detrimental process resulting in an increase in lung vascular resistance. Nebulization of sodium nitrite has been shown to inhibit HPV. The aim of this project was to investigate and compare the effects of nebulization of nitrite and different formulations of acidified sodium nitrite on acu...
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Hypoxic pulmonary vasoconstriction is a local reflex in the lung that diverts blood away from poorly oxygenated regions. Improvements in understanding of modulators of this response have led to pharmacologic methods whereby V/Q matching may potentially be improved in certain types of pulmonary pathology and during anesthesia for thoracic surgical procedures.
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ژورنال
عنوان ژورنال: Respiratory Research
سال: 2010
ISSN: 1465-993X
DOI: 10.1186/1465-9921-11-81